The RR-DGGE is a complete system for DNA mutation analysis.
Using the innovative vertical screw-clamp technology of the V-MAXI system, the RR-DGGE is fully equipped – with temperature control unit, stirrer, gradient mixer and casting accessories – to perform specific mutation analysis applications. The powerful microprocessor-controlled PID temperature control unit enables various mutation detection techniques to be undertaken between ambient temperature and 70°C, while the simple fourscrew design of the WAVE insert accelerates set up of denaturing PAGE gels.
RR-DGGE can be used to screen single-base pair changes in the following applications:
- Parallel Denaturing Gradient Gel Electrophoresis (DGGE)
- Constant Denaturing Gradient Gel Electrophoresis (CDGE)
A maximum 96-sample throughput allows detection of as many mutations within a couple hours, alleviating many of the bottlenecks associated with screening for DNA mutations.
The gradient mixer is supplied as standard to ensure efficient gradient formation by mixing and delivering high- and low-density denaturant solutions. The peristaltic pump is also recommended for delivery of linear and reproducible gradient gels.